antiplatelet aggregation o idant

Passiflora edulis Leaf Extract: Evidence of Antidiabetic …

Passiflora edulis Leaf Extract: Evidence of Antidiabetic and Antiplatelet Effects in Rats Bruno Cesar Correa Salles, Marcelo Aparecido da Silva, Lara Taniguthi, Juliane Naiara Ferreira, Claudia Quintino da Rocha, Wagner Vilegas, Pollyana Hammoud Dias, Paula Comune Pennacchi, Stella Maris da Silveira Duarte, Maria Rita Rodrigues, Maísa …

Antiplatelet drug 'resistance'. Part 1: mechanisms and ...

2009/04/01· In the first section of this two-part Review, Dr Sweeny and colleagues explore the phenomenon of 'resistance' to antiplatelet drug therapy. They discuss the various factors influencing the patient ...

Immediate Antioxidant and Antiplatelet Effect of …

2012/05/21· In a few studies, such an antiplatelet effect was early and apparently independent from the cholesterol-lowering property of statins. 5,10,28 In one of these studies, the antiplatelet effect was examined 24 hours after 10-mg 28 In our

(PDF) IN VITRO ANTI-PLATELET AGGREGATION …

2016/01/01· antiplatelet aggregation act ivity and the maximum activity was o bserved at 10 mg/ml concentration. T he standard drug aspirin showed aggregation 32.29% and inhibition 51.05 %

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Antiplatelet agents in hemodialysis | SpringerLink

2016/12/08· Patients affected by cardiovascular disease (CVD) are treated with antiplatelet agents (AA) and/or anticoagulant drugs, which are fundamental in the management of stroke, coronary atherosclerotic disease, peripheral vascular disease and atrial fibrillation. CVD is the most important cause of death in chronic renal failure …

Anti-platelet Effect of Berberine in Patients After ...

2017/12/20· The APLABE-PCI is a single-center, randomized, open-label, controlled, dose-escalating, parallel-group study, which is designed to assess the anti-platelet effect of berberine in approximately 64 patients receiving aspirin ...

The antiplatelet effects of nitrates: is it of clinical …

2020/04/23· The antiplatelet effects of nitrates: is it of clinical significance in patients with cardiovascular disease? Zhou RH(1), Frishman WH. Author information: (1)Division of Cardiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. [email protected]

Screening of anti-platelet aggregation agents from …

2008/04/01· Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS Article in Journal of Separation Science 31(6-7):1173-80 · April 2008 ...

Optimization of antiplatelet/antithrombotic therapy for ...

Role of antiplatelet therapy in secondary stroke prevention is of major significance. Antiplatelet agents predominantly in use are aspirin, clopidogrel, and combination regimes. The review focuses on the optimization of …

Antiplatelet effects – Materia Medica

2013/02/22· Posts about Antiplatelet effects written by kelly80charlie04 Actions: Anti-oxidant Anti-inflammatory Protection against ischaemic and reperfusion injury Inhibits platelet aggregation and antithrombotic effects Stimulates

Styrylpyrone-class compounds from medicinal fungi …

2011/02/09· Members of the genera Phellinus and Inonotus, including P. linteus, P. igniarius, P. ribis, I. obliquus and I. xeranticus are well-known medicinal fungi (mushrooms) and have been used in treatment ...

Some phytochemical, pharmacological and toxicological ...

Ginger (Zingiber officinale Roscoe, Zingiberacae) is a medicinal plant that has been widely used in Chinese, Ayurvedic and Tibb-Unani herbal medicines all over the world, since antiquity, for a wide array of unrelated ailments that include arthritis, rheumatism, sprains, muscular aches, pains, sore throats, cramps, constipation, indigestion, …

Antiplatelet Effectivity between Aspirin with Honey on ...

2019/10/30· Honey contains flavonoids, including hesperetin that serves as anti platelet aggregation []. With the effect of antiplatelet on honey, the researchers are interested in researching the comparison of the effectiveness of aspirin with honey as antiplatelet based on measurement of bleeding time on the tail of mice.

Enzyme Kinetics Studies of Nucleoside Diphosphate …

Coagulation, Antiplatelet, Antithrombotic, Aggregation. INTRODUCTION Platelets belong to blood cells that participate in the human primary hemostatic mechanism. Platelets need to be activated to perform all of their functions[1] ...

Antiplatelet activity of flavonoid and coumarin drugs ...

2016/12/01· All the polyphenols tested inhibited platelet aggregation. A percentage antiplatelet activity of 88.91 ± 7.98% was recorded for naringin, 48.43 ± 8.84% for naringenin, 53.83 ± 7.87% for esculetin, 54.65 ± 6.91% for fraxetin, and 25 ...

Vasculoprotective Role of Olive Oil Compounds via …

2018/12/21· Beneficial Anti-platelet Aggregation Effects of Olive Oil Compounds and Molecular Mechanisms of Action The major phenolic compounds of olive showed inhibitory effects on platelet aggregation, which is implicated in the development of endothelial dysfunction.

Anti-Thrombotic, Anti-Oxidant and Haemolysis …

aggregation ratio) aspirin by treatments were determined. At 0.25 and 0.125 mg/mof aspirin, the L PARs were 38.9% and 54.3%treatment. Only AM treatment (0.25 mgcompared with non-treatment (Table 4, Figure 2). Strong and 1 ...

Vasorelaxant and anti-platelet aggregation effects of …

Platelet aggregation plays a pivotal role in the progression of thromboembolic diseases pathogenesis (Cassar et al., 2003). Hence, a logical strategy to prevent or treat thrombosis and reduce the related cardiovascular disease events is to target platelet aggregation by drugs and/or dietary intervention ( La Rosa et al., 1990 ).

Evaluation of selected South African plant species …

cant (p ≤ 0.05) antiplatelet activity and did not differ from the control (aspirin) with EC 50 of 0.06 ± 0.01 µg/mL and 0.19 ± 0.00 µg/mL, respectively. Lower EC 50 values in the antioxidant and antiplatelet studies are indica-tive of

Coumarins and Antiplatelet Constituents from the Root …

2000/11/01· Among the isolates, terpenyl-coumarins and furoquinolines were the active constituents with antiplatelet aggregation in vitro and collinin (10) showed significant anti-HBC DNA replication activity.

Passiflora edulis Leaf Extract: Evidence of Antidiabetic …

Thus, the increase of diabetes mellitus-induced platelet aggregation has been demonstrated by different authors. 25–29) Several studies have suggested that increased platelet aggregation might be associated with alterations in ROS production which could directly influence platelet aggregation activation as well as thrombus formation and …

CAB Direct - Anti-platelet, anti-hypercholesterolemic …

Cabbage is commonly used as a vegetable in several cuisines and as a herbal remedy in many ailment conditions. In this study, some in vivo and in vitro tests were carried out. Biochemical parameters like total serum cholesterol ...

(PDF) Anti-platelet aggregation activity of walnut hull …

2017/03/01· Anti-platelet aggregation activity of walnut hull extract via suppression of ROS generation and caspase activation Azadeh Meshkini, Masoumeh Tahmasbi PII: S2005-2901(16)30171-6 DOI: 10.1016/j.jams ...

An investigation of the antiplatelet effects of …

ORIGINAL ARTICLE An investigation of the antiplatelet effects of succinobucol (AGI-1067) Stephanie A. Houston1,2, Azizah Ugusman1,3, Sukanya Gnanadesikan1, & Simon Kennedy1 1Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK, 2Manchester Immunology Group, Manchester, UK, and ...

(PDF) Antiplatelet aggregation and cytotoxic activity of ...

2015/06/10· The antiplatelet aggregation activity of the compounds was separately evaluated on collagen, adenosine diphosphate [ADP], thrombin and epinephrine induced rat platelet aggregations. The 3-(4,5 ...

Anti-Platelet Activities of Polyozellin In Vitro and In …

Anti-Platelet Activities of Polyozellin In Vitro and In Vivo Eun-Ju Yang 1 #, Sae-Kwang Ku 2 # and Jong-Sup Bae 1 * 1 College of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, Kyungpook National University, …

Antiplatelet Aggregation Activity of Walnut Hull …

The total phenolic and flavonoid content of wal hull extract was evaluated by different colorimetric techniques, using the Folin–Ciocalteu assay and aluminum chloride reagent, respectively. As shown in Fig. 1, the total phenolic and flavonoid content of each gram of dried acetone extract of wal hull was equivalent to 95.2 ± 6.29 mg gallic acid and 65.2 …